INJECTION DRUG USE ALTERS PLASMA REGULATION OF THE B CELL RESPONSE


Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progressionResearch in context

Background: Triple-negative breast cancer (TNBC) remains difficult to be targeted.SET and cancerous inhibitor of protein phosphatase 2A (CIP2A) are intrinsic protein-interacting inhibitors of protein phosphatase 2A (PP2A) and frequently overexpressed in cancers, whereas reactivating PP2A activity has been postulated as an anti-cancer strategy.Here

read more


An Exploratory Study of Autonomic Function Investigations in Hemophiliacs on Homoeopathy Medications Using Impedance Plethysmography

Background.Status of autonomic homoeostasis in hemostasic disturbances due to hemophilia needs to be studied.Objectives.To compare autonomic nervous system markers measured by heart rate variability (HRV) and blood flow variability (BFV) in hemophiliacs and healthy age-matched control population using medical analyzer system.Design.Cross-sectional

read more

The Problematics Mitigation of Forest and Land Fire District (Kerhutla) in Policy Perspective (A Case Study : Kalimantan and Sumatra in Period 2015-2019)

Forests are the source of community life.In recent years the problem of natural disasters in forest fires (Kerhutla) in two provinces in Kalimantan and Sumatra has been very detrimental to the state and local communities.Disasters are events that can be social, economic and political.Based on the results of this study it can be concluded that fores

read more